Influence of Different Methods Preparation on Platelet Activation in Stored Platelet Concentrates

Platelet transfusion therapy has played an important role in the management of patients [4]. Today, a variety of methods for the preparation of platelets for transfusion are available ,which may be due to different processing systems such as apheresis ,buffy coat and platelet rich plasma platelet concentres methods [5,6]. Processing and storage may affect both platelet quality and function and they may thus be less effective when transfused than fresh platelets [7-9]. Platelet functional assessment can be performed by a number of different methods; including cell counting, pH and markers for platelet activation.